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EUGENE, Ore. (AP) -- Sabrina Ionescu had 21 points and seven assists to become the 12th woman in NCAA history to reach 900 career assists, and No. 2 Oregon handed Colorado its first loss of the season with a 104-46 victory. The Ducks earned their fifth straight win. Oregon's lone loss was to No. 8 Louisville at the Paradise Jam on Nov. 30. The Buffaloes opened their Pac-12 slate with an 80-70 victory at Utah on Sunday. Colorado was one of just nine undefeated Div. I teams going into the game. The Buffaloes were led by Jaylyn Sherrod and Aubrey Knight with nine points apiece.